Description
Pregabalin is a medication used to treat anxiety and epilepsy. Pregabalin is also known as generic Lyrica. The drug is effective for pain caused by fibromyalgia and for nerve pain in people with diabetes, spinal cord injuries, herpes zoster, and other neuropathic pain when prescribed by a doctor.
What Is the Generic Alternative for Lyrica?
FDA-approved alternatives are Gabapentin and Cymbalta. But they are even more expensive than Lyrica. The benefit of Gabapentin is its safety for pregnant women. Nevertheless, Lyrica 150 mg price and its costs with 100 mg, 300 mg, and 75 mg are rather affordable on the Mexican pharmacy websites.
Lyrica for anxiety
Treatment of anxiety with generic Lyrica in clinical trials has shown improvements in both mental and physical symptoms of anxiety. Anxiety, restlessness, and tension decreased by more than 50% after 4-6 weeks. For anxiety disorder, large doses of the drug as prescribed by the treating physician are considered effective.
Pharmacokinetics
When taken on an empty stomach, the drug is quickly absorbed, and the maximum concentration in the blood is reached within an hour. The drug is eliminated almost unchanged, the elimination half-life is 6.3 hours. If this product does not meet your needs or interests, you may want to look at Lyrica Pregabalin 28 Tabs. Please visit this link for further information on our Anticonvulsant Drugs
Lyrica Pharmaceutical Form and Use
The average pharmaceutical form of the Lyrica generic is oral. You can buy Pregabalin to treat nerve pains and seizures with the help of capsules or suspension. It is worth noting that both tablets and liquid pharma form of the generic do not contain any smell and taste. The average package of Lyrica contains 28 tabs.
The most common content of active agents in the medication (Pregabalin gamma-aminobutyric acids) are:
- 75 mg;
- 150 mg;
- 300 mg.
Speaking about suspension, it is possible to find Lyrica 25 mg and 50 mg. The liquid pharmaceutical form is recommended for the treatment of small children. Kids aged 1 month and older can use this generic with the lowest content of the active agent to avoid overdosing and side effects.
Note that capsules should not be chewed. It is better to swallow the tablet and wash down Lyrica with enough water. Do not neglect your healthcare specialist’s recommendations. Follow the dosage plan specified by the doctor:
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Take 1-2 pills a day of the Lyrica generic during 12-20 days to reduce nerve pain-driven sensations.
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Take 1-2 pills of this medication daily to reduce or even absolutely cope with the seizures. The treatment course can last up to 5-6 months.
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Take 1 pill at bedtime to reduce anxiety, do away with insomnia, migraines, and back pain. This dosage plan is prescribed to patients with moderate chronic painful sensations.
Note that severity of the illness matters when it comes to the Lyrica generic use. Some patients with difficult medical cases and high tolerance to active agents of the drug can count on more intensive courses with Pregabalin 150 mg or 300 mg.
Lyrica Dosage for Sleep
If you have chronic insomnia, it is better to buy Lyrica and take medication for 5-10 days (at bedtime). This way, the accumulative effect is achieved. The patient is able to relax and sleep tight. After the break time (about 10-14 days), the medication therapy can be repeated but with decreased intensity.
Lyrica for Back Pain
If the pain is severe, the daily use can take place 2-3 times. The optimal interval between intakes is 8-12 hours. During this period, the generic block nerve pains successfully. Do not forget to drink enough water for better absorption of the medication.
Lyrica for Migraines
The dosage plan and use of Lyrica are similar to the previous case (backaches). If you have migraines, be ready to take the drug several times a day. Some moderate headaches can be treated with one pill at bedtime. Consult with your doctor if migraines become more intensive.
Lyrica Half-Life
This medication obtains a rather long half-life. If you are asked about how long Lyrica stays in your system, the answer is about 6-7 hours. That is why the optimal interval between doses when it comes to severe nerve pains is 8-9 hours.
Note that it is dangerous to stop taking this drug spontaneously. Attention! Never quit using Lyrica suddenly. You should cut down your dosing gradually. Ask your healthcare specialist about instructions to withdraw the medication with no side symptoms.
Lyrica Withdrawal Symptoms
If you suddenly stop using this generic, you can face real withdrawal syndromes (dry mouth, depression, fever, aches, uncontrolled aggression, etc.). It is very dangerous for your health when it comes to shallow or weak breathing. Other organisms’ reactions caused by the sudden rejection of the drug are similar to overdosing symptoms and side effects.
Lyrica: Mechanism of action
The mechanism of action of pregabalin consists of binding to an additional subunit of voltage-dependent calcium channels in the CNS, where gabapentin is irreversibly substituted. This binding presumably provides antinociceptive and anticonvulsant effects.
Is Lyrica an opioid?
Generic Lyrica is neither an opioid nor a narcotic. It is a prescription medication, an anticonvulsant that is prescribed to suppress certain types of nerve pain.
Lyrica vs Gabapentin
Generic Lyrica (Pregabalin) and Gabapentin have different side effects. Pregabalin most commonly causes dry mouth, constipation, edema, and weight gain. Gabapentin causes side effects such as difficulty speaking, fever, and convulsions.
Lyrica is absorbed faster and also begins its effects faster, so it may be more effective than Gabapentin in some cases. The maximum concentration of Gabapentin is reached in 3-4 hours, while MC of Pregabalin is an hour. It is because of the faster absorption that Pregabalin is thought to be more quickly addictive.
Although the drugs are similar, they are not interchangeable. You should not switch from pregabalin to gabapentin without a doctor’s prescription. It is convenient and easy to buy Lyrica online if you cannot find the drug in your pharmacy.
How to use Lyrica?
The dosage range is 150-600 mg/day. Usually, the dose is divided into 2-3 doses. Treatment with generic Lyrica begins with 150 mg, depending on the effectiveness and individual characteristics of the body, the dose can increase after the first week of use.
Patients with renal and hepatic insufficiency, as well as the elderly and children, require a dose adjustment as prescribed by the attending physician.
Side effects
Common side effects include:
- dizziness
- drowsiness
- headache
- increased appetite
- confusion, euphoria, decreased libido
- impairment of attention, memory, speech
- insomnia, fatigue, lethargy
- blurred vision
- dry mouth, constipation, nausea
- weight gain.
Some patients refuse to buy Lyrica online or in the local pharmacies because of side effects. But it is worth noting that most unpleasant symptoms take place if the dosage plan is improper for this or other cases. Additionally, intolerance to the active and inactive agents can matter and cause allergic reactions.
This way, patients can complain of weight gain, swelling hands, decreased libido, and other issues. Among the most common side effects that will come to an end in 5-6 days of the course (when the organism got used to the active agents of the drug) are:
- Blue-colored lips and toes;
- Vision problems;
- Confusion and weakness;
- Muscle pain;
- Trouble concentrating.
Patients also can feel swelling feet, dizziness, and blurred vision.
Lyrica Side Effects Sexually
At the beginning of the course, you can mention that your libido decreases. Do not worry, your sexual health will recover while the organism gets used to the Pregabalin active agent. Buy Lyrica 300 mg online or in the local pharmacies only in case of severe nerve pains. For moderate cases, use 100 mg, 150 mg drugs.
Does Lyrica cause weight gain?
Weight gain is one of the most common side effects of pregabalin (generic Lyrica). This symptom is observed in adults and children. In studies, the weight of patients increased by about 7% after starting to take Lyrica for 14 weeks.
Lyrica: weight gain
Causes of weight gain while taking pregabalin are increased appetite and fluid retention in the body (frequent swelling of hands, feet, and legs). Also, weight gain can be associated with higher doses and prolonged intake.
To avoid excessive weight gain while taking Lyrica it is necessary to consult a GP to reduce the dose if possible, add physical activity to daily life, and control appetite.
Interactions
Since pregabalin is eliminated from the body almost unchanged and undergoes little metabolism, it is compatible with most medications.
It is not recommended to use alcohol with generic Lyrica, because pregabalin enhances the effects of ethanol and increases alcohol intoxication. If ingestion of the drug with alcohol has already occurred, it is recommended to take a sorbent.
It is not worth taking drugs affecting the CNS. The effect of Lorazepam is enhanced by pregabalin. The drug also enhances motor and cognitive functions caused by oxycodone.
Overdose
They are similar to side effects but usually – more severe and accompanied by fever and troubled breathing. Use the drug according to your dosage plan to avoid unpleasant overdose symptoms and hormonal misfunctions.
Symptoms of overdose are severe restlessness, confusion, drowsiness, and occasionally coma. Treatment consists of general supportive measures of the body, in severe cases, hemodialysis may be required. Do not exceed the dose of 600 mg/day.
Contraindications
Contraindications to taking generic Lyrica (Pregabalin) are hypersensitivity to the active substance or excipients. In case of a hypersensitivity reaction, which is manifested by angioneurotic edema, it is necessary to immediately stop taking the medicine and consult a physician.
Lyrica 75 mg: price
Lyrica online in Mexican pharmacy has an affordable price. It is convenient to buy Lyrica online when ordering several packs of the drug at once or with other medicines. You can stock up on a full course of treatment or combine your purchase with people nearby who are also interested in medicine, then the delivery price will be much more favorable.
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