Description
Neobes Amfepramone 75 mg is an anorexigenic agent that promotes weight loss in obese patients.
Brand Name: Neobes.
Generic Name: Amfepramone.
Structure:
| Active substance | 1 tablet |
| Amfepramone | 75 mg |
Release and composition forms
The active ingredient of the drug is amfepramone hydrochloride. The component is considered an analog of amphetamine, but the compounds have different properties. Amfepramone hydrochloride looks like a white crystalline powder. It tastes bitter and dissolves well both in water and in alcohol. The drug for weight correction is available as tablets for oral administration in two dosages – 50 and 75 mg.
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Indications for the use of Neobes
- for patients without concomitant diseases – with a BMI of at least 30 kg / m2;
- for patients with risk factors – with a BMI of at least 27 kg / m2.
Indications for taking Norex Neobes
A physician may write a prescription for the pills in such indications as:
- disorders of pituitary gland function;
- thyroid abnormalities (hypothyroidism);
- adiposogenital dystrophy;
- weight gain against the background of hormone therapy;
- exogenous obesity.
Method of administration and dosage
Amfepramone is used in the treatment of obesity and body weight maintenance only as part of a complex therapy that involves lifestyle changes, including dietary restrictions and / or exercise. The duration of therapy cannot be long and is limited to several weeks.
Neobes is prescribed for oral administration, 25 mg 2-3 times a day, half an hour or an hour before meals (breakfast and lunch). With good tolerance and insufficient effect, the dose can be increased to 0.1 g per day. The course of treatment is 1.5–2.5 months. If necessary, repeat courses are carried out at intervals of 3 months.
How the drug works
Against the background of taking the drug Norex Neobes launches the following sequence of actions:
- uncontrollable appetite is suppressed;
- the patient is satiated with smaller meals;
- the daily caloric content of the diet is reduced.
The body doesn’t receive excessive amounts of nutrients during treatment. A caloric deficit is created. As a result, the fat layer is burned. The weight of an obese or pre-fat patient gradually begins to decrease.
A course of therapy with pills promotes the development of proper eating habits. After treatment, the patient no longer returns to his previous portion sizes and maintains a stable weight.
Action in the body
The active ingredient is absorbed through the gastrointestinal tract. The therapeutic effect occurs 30-60 minutes after oral administration. The spent drug is excreted by the kidneys with the urine within a day.
Amfepramone hydrochloride belongs to the group of appetite-controlling substances. It has anorexigenic and psychostimulant effects. The chemical compound affects directly the satiety center, located in the brain. The substance stimulates the cortex of the large hemispheres, practically not affecting the peripheral neurons.
Side effect of Neobes
From the side of the cardiovascular system: tachycardia, increased blood pressure.
From the side of the central nervous system: weakness, headache, insomnia, euphoria, irritability, mood deterioration.
From the digestive system: dry mouth, nausea, vomiting, constipation or diarrhea.
Allergic reactions: rash, pruritus, eyelid edema, rhinitis, conjunctivitis.
Other adverse reactions from the use of diet pills: myalgia, dysuria, polyuria; with prolonged use – alopecia, decreased potency, drug dependence.
Important: There are risks that Neobes Amfepramone may be addictive.
Possible side effects
Norex Neobes is usually well tolerated by patients. In rare cases, long-term treatment has resulted in:
- nausea;
- diarrhea;
- dry mouth;
- skin rashes;
- anxiety;
- irritability.
Taking preparations based on amfepramone hydrochloride affects the nervous system. There may be decreased concentration of attention. During treatment with Norex, don’t drive vehicles and operate complex mechanisms.
When treated with high doses, sleep disorders are possible. In order to prevent insomnia, it’s better to take Neobes tablets in the morning.
Overdose
Symptoms of Neobes overdose: tremor, hyperreflexia, tachypnea, confusion, hallucinations, collapse, convulsions in patients with epilepsy. Treatment: induction of vomiting, gastric lavage, forced diuresis; with the development of severe mental disorders – psychoactive drugs; when symptoms of respiratory failure appear – mechanical ventilation; with tachycardia – beta-blockers.
Overdose
If you follow the instructions and treat under medical supervision, the risk of overdose is minimized. In rare cases, hallucinations, toxic psychosis are possible. These are temporary conditions that go away on their own against the background of withdrawal of the drug or reduction of the daily dosage.
The effectiveness of medication treatment of obesity with the help of Norex Neobes will be higher if the patient doesn’t neglect physical activity, reduces the daily caloric content of the diet, and, if necessary, organizes days of discharge.
Take the pills for a course of up to 2.5 months. Once the weight is stabilized, stop taking them. Under indications, it’s possible to repeat the course in 3 months. Prolonged treatment can cause addiction to the active component.
Contraindications to the use of Neobes
Atherosclerosis, arterial hypertension, myocardial infarction, pheochromocytoma, pituitary adenoma, diabetes mellitus, psychosis, epilepsy, thyrotoxicosis, glaucoma, childhood (up to 12 years), hypersensitivity to amfepramone.
Neobes Amfepramone is contraindicated in pregnant women and during lactation.
Medical advice: Treatment should be carried out under the close supervision of a physician.
Contraindications to use
Norex Neobes tablets are not prescribed in the presence of the following contraindications:
- individual intolerance;
- glaucoma;
- complicated hypertension;
- thyrotoxicosis;
- myocardial infarction;
- progressive atherosclerosis;
- impaired blood supply to the brain;
- diabetes mellitus;
- epileptic seizures;
- chronic alcoholism;
- pregnancy;
- lactation.
Tablets are prescribed with caution in patients with chronic pathologies of the cardiovascular system. Use is possible outside periods of exacerbation. The minimum age limit is 12 years. Use in adolescents with hormonal or neurogenic disorders is possible in a reduced dosage under strict medical supervision.
Neobes: application
Neobes is a medication that contains the active ingredient amfepramone, a central nervous system stimulant used to treat obesity and overweight. The drug acts as an appetite suppressant that helps reduce feelings of hunger and control food intake. Amfepramone hydrochloride is indicated for the short-term treatment of obesity in combination with a low-calorie diet and exercise. Neobes pills are indicated for patients with a body mass index (BMI) of 30 or higher, or a BMI of 27 or higher with other risk factors associated with obesity, such as diabetes, high blood pressure, or high cholesterol.
Neobes: side effects
Neobes (Amfepramone) may cause the next side effects:
- insomnia;
- nervousness;
- dizziness;
- headache;
- dry mouth;
- constipation;
- diarrhea;
- increased heart rate;
- high blood pressure;
- palpitations;
- blurred vision;
- changes in libido or sexual function.
It is important to note that Neobes can be addictive and can cause abuse, so it should only be used under the guidance of a physician. In addition, some people may have an allergic reaction to the Neobes pills, with symptoms such as rashes, itching, swelling, or difficulty breathing. If you experience any serious or persistent side effects, you should see your doctor immediately.
Neobes: weight loss
Neobes, like other central nervous system stimulants, work by stimulating neurotransmitters such as noradrenaline, dopamine, and serotonin, which are involved in regulating appetite and metabolism. Amfepramone increases the levels of these neurotransmitters in the brain, which leads to a decrease in appetite and an increase in metabolism, which can lead to weight loss.
Amfepramone can also increase blood levels of epinephrine, which helps mobilize fat stores in the body and increase energy expenditure.
How much weight can I lose?
Neobes 75mg is used as an adjunct to diet and exercise to reduce weight in obese or overweight people.
However, the number of pounds that can be lost with Neobes can vary depending on many factors, such as initial weight, lifestyle, diet, health status, and many others.
Studies show that when used correctly, you can lose 5-10% of your initial weight within 3-6 months with proper diet and exercise.
Contraindications
Neobes pills are not recommended to be prescribed for such diseases:
- Individual intolerance to amphetamines and other components of the drug.
- Hypertension – may increase blood pressure
- Cardiovascular disease – the drug may worsen the condition of the heart and blood vessels, so it is not recommended for people with heart conditions such as arrhythmia, angina pectoris, etc.
- Depression and other mental disorders
- Glaucoma
- Hyperthyroidism
- Pregnancy and breastfeeding and children under the age of 12
This is not a complete list of contraindications, so it is important to consult with your doctor before starting Neobes.
Dosage
Neobes 75mg is taken once or twice a day before meals, in the morning, or at lunchtime. However, the dosage may vary depending on your body’s individual reaction to the drug, as well as your doctor’s recommendations.
With long-term use, Neobes may also develop a tolerance to its effects, which may lead to the need to increase the dose to achieve the desired effect. This may also increase the risk of addiction. Neobes should be taken strictly as recommended by your doctor and not exceed the recommended dose.
Neobes and alcohol
Neobes is an obesity medication that contains amphetamine stimulants. Neobes’ interaction with alcohol can be very dangerous.
For one thing, alcohol can increase the risk of unwanted side effects associated with the CNS stimulant drug, such as insomnia, nervousness, anxiety, elevated blood pressure, and tachycardia. In this case, the interaction may worsen the patient’s health.
On the other hand, Neobes can intensify the effects of alcohol on the nervous system, which can lead to more serious problems such as poor coordination of movements, drowsiness, dizziness, and sluggish reactions.
The combination of Neobes and alcohol is not recommended and should be avoided. If you have taken Neobes and alcohol, you should seek immediate medical attention as it may be dangerous to your health.
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