Description

Sydolil (Ergotamine/ Caffeine / Acetylsalicylic acid) is a combination medicine prescribed for migraines.

1 pack of 36 tablets.

Migraine is the primary form of headache, a chronic neurological disease, manifested by attacks of headache, chronic daily or almost daily headache (chronic migraine), as well as a number of non-painful manifestations.

Brand name: Sydolil.

Generic name: Ergotamine + Caffeine + Aspirin.

If this product does not meet your needs or interests, you may want to look at Ritalin Methylphenidate. Please visit this link for further information on our Other Drugs

Sydolil composition:

Manufacturer: Siegfried Rhein.

Pharmacological action – anti-migraine.

The effect of Sydolil is associated with the vasoconstrictor effect of ergotamine and the improvement in brain function under the influence of caffeine.

Sydolil indications

• Migraine of various origins;
• Arterial hypotension.

Tablets can also sometimes be used to lower intracranial pressure in vascular, traumatic and infectious lesions of the central nervous system.

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Contraindications

Sydolil is primarily contraindicated in people with hypersensitivity to any of the ingredients.

Sydolil is contraindicated in pregnancy as Ergotamine may have a negative effect on the fetus. So, during lactation, the medicine is prohibited, since it can penetrate through milk.

Also:

• Renal failure;

• Liver failure;

• Patients with vascular disorders;
• Sick with flu or chickenpox, children under the age of 14;
• Raynaud’s disease;
• Buerger disease (Thromboangiitis obliterans);
• For bleeding or bleeding problems.

Side effects of Sydolil

Be sure to familiarize yourself with all the risks and possible adverse reactions before using the medicine.

It was reported that most often patients experienced dizziness or nausea. Allergy to any of the components of Sydolil may cause itching and swelling. Since the drug contains caffeine, insomnia is a frequent adverse reaction.

Other serious side effects include:

• Vomiting;
• Muscle pain in the limbs;
• Hypesthesia and paresthesia of fingers and toes;
• Chest pain;
• Tachycardia;
• Bradycardia.

Dosage and method of administration of Sydolil

The dose is prescribed by the doctor depending on the general state of health and indications.

The tablets are taken orally. You should take 1-2 tablets, depending on the severity of the disease. If pain persists, then take the medicine every half hour. Attention: the maximum dose is 6 tablets per day.

What is Sydolil medication used for?

Sydolil is a combined antimigraine drug. This medicine consists of three substances: acetylsalicylic acid, caffeine, and ergotamine.

Ergotamine causes a vasoconstrictor effect. Caffeine accelerates the absorption of ergotamine and enhances the effect of ergot alkaloids in treating migraine. Caffeine also causes stimulation of the CNS, mainly the cortex, respiratory and vasomotor centers. It increases mental and physical performance and reduces sleepiness and fatigue.

Caffeine has a pronounced cardiotonic effect: it increases strength and heart rate and raises blood pressure in hypotension.

Aspirin (acetylsalicylic acid) has analgesic, anti-inflammatory, and anti-fever effects.

Sydolil: ¿Para qué sirve

Sydolil is prescribed for the following conditions:

• Acute migraine attacks (also those accompanied by aura);
• Migraine-like headaches of vascular genesis;
• Arterial hypotension;
• As an agent that lowers intracranial pressure in case of vascular, traumatic, and infectious CNS lesions.

It is recommended to take the drug at the beginning of an attack. Before using, consult a physician and tell him about the accompanying chronic diseases and the intake of other drugs.

Dosage and administration

Orally, 1-2 tablets 2 times a day during a headache attack, then 1 tablet 2-3 times a day for several days (up to 1 month). The maximum single dose is 2 tablets, the daily dose is 4 tablets.

It is not recommended to use Sydolil (Mexico) for a long time (to avoid ergotism). After 7 days of use, in cases requiring longer treatment, take a break (3-4 days).

Contraindications

Consult your doctor before use because Sydolil medication has various contraindications:

• Hypersensitivity to the components of the drug
• Leukopenia
• Adenoma of prostate gland
• Peptic ulcer
• Mechanical stenosis of the gastrointestinal tract
• Megacolon
• Tachyarrhythmias
• Severe cerebral sclerosis
• Vascular stenosis
• Angina pectoris
• Coronary heart disease
• Arterial hypertension
• Peripheral circulatory disorders
• Temporal arthritis
• Stroke
• Hyperexcitable state
• Sleep disturbance
• Narrow-angle glaucoma
• Genetically determined glucose-6-phosphate dehydrogenase deficiency (manifested as hemolytic anemia)
• Acute hepatic porphyria
• Renal and hepatic diseases
• Sepsis
• Hyperthyroidism
• Nutritional deficiencies or disorders
• Hemiplegic or basilar migraines
• Age over 65 years of age

Driving vehicles and operating moving mechanisms are not recommended during treatment.

Sydolil: side effects

Despite the effectiveness of Sydolil tablet 400 mg, adverse reactions are possible:

• CNS side: sleep disorders, increased excitability; with prolonged use, the development of habituation is possible.
• Cardiovascular system: transient tachycardia, ECG changes, increased BP, heart pain, bradycardia, muscle pain, decreased pulsation in extremities, paresthesias in extremities (most of these effects are associated with increased peripheral vascular tone).
• Digestive system: nausea, vomiting; rarely diarrhea.

If the first signs of such effects appear or if pregnancy is suspected, it is necessary to consult a physician immediately. There is no data on possible addiction to the drug.

Peculiarities of use

Do not use the drug to prevent a migraine attack.

Patients taking Sydolil medication should periodically monitor blood values. When taking it systematically, the prescribed doses should be strictly adhered to avoid the development of ergotism phenomena: spasm of peripheral blood vessels. Ergotism is manifested by decreased sensitivity and paresthesias in the lower extremities, a feeling of “tingling” and numbness, cyanosis of the skin, most often in the fingers, weakened pulsation, as well as CNS disturbances – spasms, cramps, headaches, and dizziness.

Sometimes patients complain of pain in the heart, and disturbance of the normal heart rhythm. If such symptoms occur, stop taking the drug immediately and consult a doctor.

Dosing regimen

Sydolil should be taken at the beginning of a migraine attack. It is recommended to take 1-2 Sydolil tablets 400 mg. If the condition does not improve after 30 minutes, you can take 1-2 more tablets.

The maximum daily dose is not more than 4 tablets, and the maximum dose during one week is not more than 10 tablets.

It is not recommended to use the drug for a long time. If long-term treatment is necessary, take a break for 3-4 days after 7 days.

Precautions

The drug is not intended for migraine prophylaxis. Patients with bronchial asthma, chronic respiratory diseases, or allergic rhinitis, as well as those who have any manifestations of hypersensitivity reactions.