How does Methylphenidate work?

Generic Methylphenidate is used to treat patients with attention deficit hyperactivity disorder, also called ADHD. The drug inhibits the reuptake of dopamine and noradrenaline. The use of the drug increases their concentration in the synaptic cleft.

The action of the drug

The action of Methylphenidate hydrochloride tablets comes within 15-30 minutes. The duration of effect is from 3 to 4 hours. The duration of action of the drug is also influenced by the individual characteristics of patients. At the end of the effect, ADHD symptoms may appear more frequently.

Dosage of the medicine

Methylphenidate should be taken only after consultation with the GP. The dosage should be set individually. The optimal effect is related neither to the plasma concentration nor to the weight of the patient.

The drug is not used for children under 6 years of age. The only exception to the prescription of the drug in children under 6 years of age may be prescribed by a physician. The initial single dose may be 2.5 or 5 mg. The dose is then usually increased by 5-10 mg each week until the maximum effect of treatment is achieved.

Adults need an average of 20-30 mg per day. In severe cases, your doctor may increase the dose to 60 mg. In mild disease, the daily dosage of the medication may be 5-10 mg, which is also determined by the doctor.

The daily dose is often divided into two or three separate doses. A single dose for adult patients is frequently 10 mg, and for children over 6 years of age, the optimal single dose is 5 mg.

Tradea LP

Tradea is used in the therapy of hyperactivity and attention deficit disorder. It is a powerful CNS stimulant that is prescribed to patients with narcolepsy, apathy, complications after a stroke. It is possible to use for children and adults.

Active ingredient and product forms

The active ingredient of Tradea Medication is methylphenidate in hydrochloride form. The substance was first synthesized in 1944, and since 1961, it began to be used in the United States to treat hyperactivity. In chemical nature, it is a methyl ester.

Methylphenidate is a psychostimulant, a derivative of piperidine and phenylethylamine. The substance is absorbed into the systemic bloodstream through the gastrointestinal tract. Maximum bioavailability is 50%, average - 30%. The therapeutic effect lasts for 10-12 hours. The active substance is metabolized in the liver and excreted with urine through the kidneys.

The drug is available in two dosages:

• Tradea 10 mg for children;
• Tradea 54 mg for adults.

Form release - tablets for oral administration, packed in cartons.

Pharmacological action

Tradea medication is a psychopharmacological agent, the active ingredient is methylphenidate hydrochloride. It has a stimulating effect on the central nervous system, cerebral cortex, and subcortical structures.

The mechanism of action of the drug is associated with blocking the reuptake of noradrenaline and dopamine in the presynaptic area of neurons and increasing the release of these monoamines into the extraneuronal environment.

Tradea lp is an indirect chemical compound of dopamine and norepinephrine that strongly influences the action of these neurotransmitters in motor centers and increases attention. It acts by inhibiting dopamine reuptake to synaptic neurons in cortical and subcortical regions.

Pharmaceutical action

Tradea is well and immediately absorbed, but bioavailability is only 10-50%, due to the effect of passing through the liver. The maximum concentration of the active substance in the blood is reached after 1 – 2 hours. Up to 15% is bound to the blood plasma proteins. Excreted with urine.

This instruction to the drug is for information purposes only and is not a recommendation for self-treatment. The dosage and duration of treatment should only be prescribed by your doctor.

Brintellix is an antidepressant that is prescribed for the treatment of depressive disorder in adult patients. The active ingredient of the drug is vortioxetine hydrobromide. One tablet contains 10 mg of the active substance.

Pharmacological action

Improvement of the condition in depressive disorder is possible due to the mechanism of direct modulation of receptor activity. The active substance of Brentellix inhibits the serotonin transporter. The efficacy of the drug increases when a larger dose is taken. The 5-20 mg medication has been shown to have an effect on most depressive symptoms on the MADRS scale and anxiety disorders on the HAM-A scale. Brintellix helps improve the condition of patients diagnosed with a severe course of depression. The medication acts on cognitive function. It normalizes the quality of life. A safe dose of the active ingredient per day is 5-20 mg. There is no drowsiness or insomnia when taking it. After withdrawal, there is no withdrawal syndrome during long-term or short-term use.

Ritalin instructions for use

Ritalin 10 mg belongs to the group of psychostimulants of non-amphetamine type. The drug has a stimulating effect on the body. It is used in pediatrics to treat children with attention deficit syndrome or hyperactivity disorder. When tolerance develops and in case of uncontrolled use, the substance causes stable dependence.

What are the indications for the use of Ritalin?

Psychiatrists and neurologists often prescribe this medicine for some pathologies of the nervous system. This category includes:

• Narcolepsy;
• CNS depression after taking medications and psychotropic substances;
• Impairment of concentration and attention;
• Depressive states.

Although it is possible to buy Ritalin online in an online pharmacy, the drug is not dispensed without a doctor's prescription, because it has side effects and is addictive.

Effects of the drug on the body

Ritalin causes the following reactions in the body:

• Production of norepinephrine is increased, which has a stimulating effect on the nervous system. This effect helps to fight depression;
• The drug improves concentration;
• It tones the body;
• After a course of therapy, the teenager gains self-confidence, self-esteem increases, and complexes disappear.

Even one tablet causes euphoria, which lasts for a long time. It increases blood pressure, but much less than Amphetamine.