Description

Mazindol inhibits appetite, so it is prescribed to improve the effectiveness of a low-calorie diet. There is a satiety center in the brain in the hypothalamus, which is directly affected by the main component of the drug. It acts on the adrenergic systems, which allows the effect of reducing the need for food.

Pharmacology and pharmacokinetics

The drug belongs to the amphetamine group, so it is an inhibitor of noradrenaline reuptake and inhibits dopamine and serotonin reuptake.

The maximum concentration of the drug in blood plasma is reached after 2-4 hours. The elimination half-life is about 33-35 hours. The effect of appetite reduction lasts up to 8-15 hours.

Composition and product form

The active ingredient of the drug is mazindol. According to its chemical structure, it is a sympathomimetic amine. The properties of the compound are close to those of amphetamine. In the USA and Mexico, the appetite suppressant is available in the form of tablets of 30 pieces in a package.

Two dosages are possible:

• Mazindol 1 mg;
• Mazindol 2 mg.

Spent active substance is excreted mainly through the kidneys with the urine. If this product does not meet your needs or interests, you may want to look at Itravil-IFA Clobenzorex. Please visit this link for further information on our Weight Loss Pills

Peculiarities of application

Mazindol online can be purchased for the treatment of patients from 12 years old. Administration of the drug is started after consultation with a doctor and making an individual weight loss plan. The course of treatment begins with the prescription of 0.5 mg of the drug during the first 4-5 days.

The drug is taken during the first meal to increase satiety and reduce the desire to eat a few hours after breakfast.

After the start of treatment, the dose is increased, taking one or two Mazindol tablets. If the drug is taken twice a day, it is better to take one tablet at breakfast and one at lunch. To avoid negative effects on the body, you should not exceed the maximum daily dose, which is 3 tablets per day.

The course of treatment with Mazindol should not be longer than 12 weeks because usually this period is sufficient to obtain the desired result without compromising health. In addition, remember that after 8-10 weeks there may be an addiction to the drug, which reduces its effectiveness.

Principle of action in the body

The active substance enters the systemic bloodstream through the digestive tract. Mazindol affects directly the cardiovascular system and the CNS. Against the background of taking mazindol 2mg:

• The transmission of nerve impulses is partially blocked;
• Activates the satiety center located in the hypothalamus;
• Blocks the reuptake of the hormones adrenaline and serotonin;
• Increases heart rate;
• Blood pressure rises.

Systematic taking of the pills causes false satisfaction of the hunger center. The patient’s appetite decreases; as a consequence, the patient reduces portions and chooses less caloric foods. Gradually, the correct eating behavior takes hold. The weight continues to decrease even after the treatment has ended. In addition, due to the effect on the endocrine system provides a moderate antidepressant effect.

Indications for use

Mazindol LOSE-IFA is indicated for adults and adolescents over the age of 12 years for next cases:

• Obesity against the background of uncontrolled appetite;
• Neurogenic and endocrine disorders;
• Weight gain after treatment with hormones;
• Duchenne muscular dystrophy.

Direct indication for the prescription of tablets is a body mass index exceeding 27-30 units. The minimum duration of intake – 30 days, the maximum course – three months. Severe obesity can be repeated up to twice a year.

Contraindications for the appointment of Mazindol

Tablets shouldn’t be used with the following contraindications:

• age less than 12 years;
• pregnancy;
• lactation;
• arrhythmia;
• heart failure;
• glaucoma;
• severe kidney and liver abnormalities;
• hyperexcitability of the CNS;
• drug addiction – current or in the anamnesis;
• individual intolerance.

Mazindol is prescribed with caution in minimal dosages in diabetes mellitus, epilepsy, anxiety disorders, thyroid abnormalities.

Contraindications

Do not take the drug with increased intraocular pressure – glaucoma.

Renal, hepatic and heart failure are also in the list of contraindications.

The drug is not suitable for the treatment of patients with arrhythmia, increased excitability.

The drug should not be combined simultaneously with MAO inhibitors. Therefore, if you are taking any medicine, and you want to order Mazindol online, please talk to your doctor or our pharmacist.

This medicine of the amphetamine group should not be taken if the activity requires high concentration: driving vehicles and operating machinery.

The administration is contraindicated in patients with a history of drug, alcohol, and medicines addiction. Also, the drug should not be used to treat patients with abnormalities of the nervous system, and depressive states. The drug should be used with caution to treat patients with a history of cardiovascular disease or the acute phase of the course.

Mazindol: side effects

In a control group of patients who took the drug for 12 weeks, the following adverse reactions were detected in isolated cases:

• Dry mouth, nausea
• Dizziness
• Sleep disturbance
• Frequent urination
• Increased sweating
• Allergies
• Increase in BP
• Constipation

If side effects occur after taking this medicine, the dose should be reduced or the medicine should be stopped completely. Side effects appear more often at the beginning of treatment and disappear over several weeks. Severe allergic reactions have been found in only one patient out of 60.

Side effects

Against the background of a course of taking tablets with Mazindol 2mg in the composition, the following symptoms are possible:

• headaches;
• dizziness;
• dry mouth;
• nausea;
• urinary retention;
• sleep disturbances;
• excessive sweating;
• skin rash;
• tachycardia.

If persistent side effects occur, it’s recommended to reduce the daily dosage and inform the attending physician. The drug is taken with caution since the active ingredient is addictive. A decrease in effectiveness by the end of the course isn’t excluded.

Overdose

A significant increase in the dose is fraught with the intoxication of the body with mazindol. Characteristic symptoms are hallucinations, confusion, shortness of breath, palpitations, tremors of extremities. In case of overdose, emergency medical assistance is needed.

Mazindol vs. Phentermine

Both drugs belong to the amphetamines group, so they have similar effects. Phentermine, unlike Mazindol, is not recommended to be taken in the evening because of the risk of insomnia. Phentermine cannot be used to treat patients under the age of 16 years, and Mazindol can be taken by obese patients from 12 years old.

Mazindol is more convenient to take since it can be taken with food. Phentermine should be taken 1-2 hours before breakfast and lunch.

Mazindol does not cause euphoria in therapeutic doses. Such an effect may occur only when taking a large dose. Unlike Phentermine, it doesn’t cause a pronounced withdrawal syndrome during an abrupt stop of treatment.

Mazindol: Weight loss

The medication is used to lose weight and improve the general condition of patients with a body mass index over 30. It is also effective for patients with a body mass index of 27 and above and the risk of complications due to excess weight: diabetes, and high blood pressure. To lose weight in the short term and avoid addiction, you need to combine medication with a low-calorie diet, moderate regular physical activity.

Mazindol 1 mg

To get the desired effect, 2 mg per day is prescribed with a split of two doses if the patient is 40 kg or less overweight. If the patient is over 50 kg, then 4 mg/day is prescribed. In such a case, two 1 mg tablets may be taken twice.

Mazindol vs. Phentermine

Mazindol and Phentermine are two prescription medications used for weight loss. However, they belong to different classes of drugs and act somewhat differently.

Lose Mazindol is a sympathomimetic amine that is classified as an anorectic. It works by stimulating the release of norepinephrine, a neurotransmitter that suppresses appetite and increases metabolism. Mazindol is usually prescribed for short-term use (up to 12 weeks) to help people lose weight.

Phentermine is also a sympathomimetic amine that is classified as an anorectic. It works by suppressing appetite and increasing metabolism. Like Mazindol, Phentermine is usually prescribed for short-term use (up to 12 weeks) to help people lose weight.

In general, Phentermine is considered more effective for weight loss than Mazindol. However, both drugs can cause side effects such as dry mouth, headache, dizziness, and insomnia. In addition, both medications can be addictive and should only be used under the guidance of a physician.

It is important to note that weight loss medications are not the only solution to weight loss, and should be used in conjunction with a healthy diet and exercise program. In addition, weight loss medications should only be used by people who are obese (BMI 30 or higher) or overweight (BMI 27 or higher) and have other conditions such as diabetes or high blood pressure.

Mazindol – weight loss

Mazindol is a medication used to treat obesity that helps you lose weight by reducing appetite and increasing satiety. Mazindol belongs to a class of anorectic drugs that are also known as appetite suppressants or weight loss agents.

Mazindol 2mg is used only by prescription and only for short-term use (usually not more than a few weeks). The drug is used in conjunction with a proper lifestyle, such as diet and increased physical activity. You can order Mazindol online at our online pharmacy.

Mazindol – Side effects

Lose Mazindol, like any medication, can have side effects. Some of the common side effects of Mazindol include:

• headache;
• insomnia;
• dry mouth;
• nausea and vomiting;
• constipation;
• dizziness;
• nervousness or restlessness;
• blurred vision;
• elevated blood pressure;
• rapid heartbeat.

Serious side effects of Mazindol that require immediate medical attention include:

• suicidal thoughts or behaviors;
• signs of an allergic reaction, such as difficulty breathing, hives, or swelling of the face, lips, tongue, or throat;
• hallucinations or delusions;
• chest pain or a feeling of tightness;
• difficulty breathing or shortness of breath;
• seizures;
• signs of liver problems, such as yellowing of the skin or eyes, dark urine, or abdominal pain.

It is important to discuss with your doctor any side effects you have had while taking Mazindol or if you have any concerns about the medicine. Your doctor will determine if the medicine is suitable and monitor possible side effects.

How many pounds can I lose with Mazindol?

The effect of losing Mazindol can be individual and depends on various factors such as the initial weight, lifestyle, diet, age and health of the person. In general, the weight loss from using Mazindol can be in the range of 5 to 10% of the initial weight within a few weeks or months.

How to take

Mazindol is usually taken orally once a day, in the morning, half an hour before breakfast, with a glass of water. The initial recommended dose is 1 mg/kg patient weight per day.

It is important to follow the recommended dosage, not to exceed it and not to prolong the course of treatment without the doctor’s consent. If side effects occur, it is necessary to consult a doctor immediately.

Can you drive a car while taking medication?

One of the side effects of Mazindol is fatigue and drowsiness. If a person takes Mazindol and experiences these side effects, they may become less alert and have slower reactions on the road, which increases the risk of an accident.

Therefore, if you are taking Mazindol, it is important not to get behind the wheel until you are sure that you are not experiencing these side effects. It is important to follow your doctor’s instructions and not exceed the recommended dose of the medication to minimize the risk of side effects and keep you safe on the road.

Mazindol and diabetes mellitus

Mazindol use may be contraindicated in patients with diabetes, as this medication may increase blood glucose levels. Mazindol can increase the excretion of glucose in the urine, which can lead to hyperglycemia (high blood sugar levels).

Patients with diabetes who take Mazindol should have their blood glucose levels constantly monitored and follow their doctor’s instructions. Mazindol should be avoided without consulting a doctor, especially if the patient has diabetes mellitus or other health problems that may affect its effectiveness and safety.

In general, the use of Mazindol for weight management in patients with diabetes may not be desirable and requires special attention and monitoring by the physician. Instead, strategies that include a healthy diet and physical activity, combined with physician consultation and appropriate treatment, are recommended for weight management and diabetes control.